Formulation of Metformin-Loaded Alginate Microspheres by Ionotropic Gelation-Aerosolization Technique
نویسندگان
چکیده
منابع مشابه
Evaluation of furosemide-loaded alginate microspheres prepared by ionotropic external gelation technique.
Alginate microspheres containing furosemide were prepared by the ionotropic external gelation technique using Ca2+, Al3+ and Ba2+ ions. The incorporation efficiency of the prepared microspheres ranged between 65% and 93%. The effect of sodium alginate concentration, cross-linking ions and drying conditions was evaluated with respect to entrapment efficiency, particle size, surface characteristi...
متن کاملFormulation of Ibuprofen Beads by Ionotropic Gelation
Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...
متن کاملFormulation of Ibuprofen Beads by Ionotropic Gelation
Microencapsulation has become a common technique in the production of controlled release dosage forms. Many results have been reported, concerning the use of alginate beads as controlled release drug formulations. Alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. Ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...
متن کاملPreparation of Microspheres of Diclofenac Sodium by Ionotropic Gelation Technique
Diclofenac sodium is a non-steroidal anti-inflammatory drug used in the treatment of arthritis. Treatment with NSAIDs is observed to have gastro intestinal side effects and the formulation of Diclofenac sodium using biodegradable and biocompatible polymer in the form of microspheres is expected to decrease GI side effects. In the present study, different microsphere formulations of Diclofenac S...
متن کاملFormulation of mucoadhesive microspheres of rosiglitazone maleate and its in vitro evaluation using ionotropic gelation technique
Aim: The objective of the present study is to design and evaluate mucoadhesive microspheres for oral controlled release. Materials and Method: Rosiglitazone maleate microspheres with a coat consisting of alginate and a mucoadhesive polymer sodium carboxymethylcellulose, carbopol 934P and hydroxypropylmethylcellulose were prepared by an orifice-ionic gelation process. The microspheres were evalu...
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ژورنال
عنوان ژورنال: Sains Malaysiana
سال: 2020
ISSN: 0126-6039
DOI: 10.17576/jsm-2020-4910-17